Matrixyl Synthe-6: Wrinkle Filling Peptide

Most anti-aging peptides do one thing: boost collagen production. Matrixyl Synthe'6 does six. This third-generation peptide from Sederma takes a broader approach to skin repair, stimulating not just collagen but five other structural proteins that fill wrinkles from the inside rather than simply smoothing the surface.

The science behind it is straightforward. Skin aging happens when the extracellular matrix—the scaffolding that keeps skin firm and plump—breaks down faster than the body can rebuild it. Matrixyl Synthe'6 addresses this by mimicking matrikines, the messenger molecules that tell skin cells to produce more structural components. The result: wrinkles get smaller, skin gets firmer, and the improvement happens where it matters most—in the dermis itself, not just on the surface.

This article breaks down what Matrixyl Synthe'6 is, how it works, what the research shows, and how it compares to other peptides in the Matrixyl family. No hype, no oversimplification—just the science translated into language that makes sense.

Quick Facts
What Is Matrixyl Synthe'6?
The Six-Component Mechanism
What the Research Shows
Matrixyl Family Comparison
How to Use Matrixyl Synthe'6
Safety and Side Effects
Frequently Asked Questions
The Bottom Line
References

Quick Facts

Attribute	Details
INCI Name	Palmitoyl Tripeptide-38
Common Names	Matrixyl Synthe'6, Pal-KMO₂K
Peptide Sequence	Pal-Lys-Met(O₂)-Lys
Molecular Formula	C₄₆H₈₈N₆O₁₀S
Developer	Sederma (Croda)
Year Released	2012
Peptide Class	Signal peptide, matrikine-mimetic
Primary Mechanism	Stimulates 6 ECM components
Targets	Collagen I, III, IV, fibronectin, hyaluronic acid, laminin-5
Typical Concentration	2% in finished products
Solubility	Water-soluble
pH Stability	3.0-7.0
Clinical Evidence	Multiple human studies

What Is Matrixyl Synthe'6?

Matrixyl Synthe'6 is a synthetic lipopeptide developed by Sederma, a French biotechnology company that specializes in cosmetic active ingredients. Released in 2012, it represents the third generation of the Matrixyl peptide family, following the original Matrixyl (palmitoyl pentapeptide-4) and Matrixyl 3000 (a combination of palmitoyl oligopeptide and palmitoyl tetrapeptide-7).

The active ingredient is palmitoyl tripeptide-38, a small peptide chain consisting of three amino acids—lysine, oxidized methionine (methionine sulfone), and lysine—attached to a palmitic acid tail. This sequence, abbreviated as Pal-Lys-Met(O₂)-Lys or Pal-KMO₂K, is derived from a naturally occurring tripeptide found in collagen VI and laminin, two proteins that form part of the skin's structural network.

The Lipopeptide Advantage

The palmitoyl (palmitic acid) group isn't just decoration. This 16-carbon fatty acid tail improves the peptide's ability to penetrate the skin's lipid barrier. Peptides are naturally hydrophilic—they prefer water environments—but skin is protected by a lipid-rich barrier that repels water-loving molecules. Adding a lipophilic tail to the peptide creates an amphipathic molecule that can cross both lipid and aqueous barriers more efficiently.

Once the peptide reaches the dermis, it functions as a matrikine-mimetic compound. Matrikines are small peptide fragments released when structural proteins in the extracellular matrix (ECM) break down. These fragments act as signals, telling fibroblasts—the cells that produce collagen and other structural proteins—to ramp up production to repair damage. Matrixyl Synthe'6 mimics this signaling process, essentially tricking the skin into thinking it needs to rebuild itself.

Why "Synthe'6"?

The "6" in Matrixyl Synthe'6 refers to the six major structural components of the skin matrix that this peptide stimulates:

Collagen I — The most abundant collagen in skin, providing tensile strength
Collagen III — Produced early in wound healing, provides elasticity
Collagen IV — Forms the basement membrane at the dermal-epidermal junction
Fibronectin — Helps cells adhere to the ECM and guides tissue repair
Hyaluronic acid — A glycosaminoglycan that holds up to 1,000 times its weight in water
Laminin-5 — A key component of the dermal-epidermal junction that anchors the epidermis to the dermis

This multi-target approach sets Matrixyl Synthe'6 apart from most anti-aging peptides, which typically focus on just one or two components of the ECM.

The Six-Component Mechanism

To understand how Matrixyl Synthe'6 works, it helps to understand what happens when skin ages. The extracellular matrix—the network of proteins and sugars that gives skin its structure—degrades over time. Collagen production slows, fibers become disorganized, and the dermal-epidermal junction (DEJ) weakens. Wrinkles form because there's less structural support holding the skin up from beneath.

Matrixyl Synthe'6 targets this breakdown at multiple points.

Collagen Stimulation: Three Types, One Peptide

Most collagen-boosting peptides focus on collagen I, the most abundant type in skin. Matrixyl Synthe'6 goes further by stimulating three types of collagen:

Collagen I makes up about 80% of dermal collagen and provides the structural foundation that keeps skin firm. According to in vitro studies, Matrixyl Synthe'6 increased collagen I synthesis by 105% after five days of twice-daily applications at 2% concentration.
Collagen III is produced during the earliest phases of wound healing and tissue repair. It provides elasticity and is more abundant in younger skin, declining with age in favor of stiffer collagen I. Studies show collagen III synthesis increased by 104% with the same treatment protocol.
Collagen IV doesn't form fibers like collagen I and III. Instead, it forms a mesh-like network in the basement membrane, the thin layer that separates the epidermis from the dermis. It plays a critical role in wound healing by interacting with keratinocytes (the main cells of the epidermis) and promoting their proliferation after injury. Collagen IV synthesis increased by 42% in the same studies.

This combination is important because different collagen types serve different functions. Boosting just collagen I might improve firmness but won't necessarily improve elasticity or strengthen the DEJ. Matrixyl Synthe'6's broader stimulation addresses multiple aspects of skin structure simultaneously.

Strengthening the Dermal-Epidermal Junction

The dermal-epidermal junction is where the epidermis (the outer layer of skin) meets the dermis (the deeper structural layer). In young skin, the DEJ has a complex, undulating structure with finger-like projections that increase the surface area and provide a strong anchor point. With aging and sun damage, this structure flattens, weakening the connection between layers and contributing to sagging and wrinkling.

Matrixyl Synthe'6 targets two key components of the DEJ:

Laminin-5 (also called laminin-332) is a protein that forms part of the anchoring filaments connecting the epidermis to the basement membrane. It's essential for epithelial cell adhesion, migration, and differentiation. Studies show that palmitoyl tripeptide-38 stimulates laminin-5 synthesis, strengthening the dermal-epidermal junction and improving the skin's structural integrity.
Fibronectin is a glycoprotein that helps cells adhere to the extracellular matrix. It plays a critical role in wound healing by providing a temporary scaffold for cell migration and tissue reconstruction. In vitro studies show that Matrixyl Synthe'6 boosts fibronectin production, which contributes to improved skin repair and resilience.

Hyaluronic Acid: The Hydration Component

While the collagen and structural proteins provide firmness and support, hyaluronic acid (HA) provides volume and hydration. HA is a glycosaminoglycan—a type of sugar molecule—that can bind up to 1,000 times its weight in water. In skin, it fills the spaces between collagen fibers, plumping the dermis and keeping wrinkles from deepening.

HA levels decline with age, contributing to the thinning and drying of skin. Matrixyl Synthe'6 stimulates fibroblasts to produce more hyaluronic acid, which helps restore volume and hydration from within rather than just applying it topically.

The HSP47 Connection

One lesser-known aspect of Matrixyl Synthe'6's mechanism involves heat shock protein 47 (HSP47), a chaperone protein that helps collagen molecules fold and assemble correctly. Without proper folding, collagen can't form the organized fibers needed for structural support.

According to Sederma's technical literature, Matrixyl Synthe'6 works with HSP47 to manage the architectural organization of collagen molecules, allowing for complete maturation and stabilization of fibers. This isn't just about making more collagen—it's about making better, more functional collagen that can actually improve skin structure.

What the Research Shows

The clinical evidence for Matrixyl Synthe'6 comes from multiple sources: in vitro studies on cultured skin cells, ex vivo studies on skin tissue samples, and in vivo clinical trials on human volunteers.

In Vitro Studies: Quantifying ECM Production

The most detailed mechanistic data comes from in vitro studies on cultured fibroblasts. In these experiments, researchers applied palmitoyl tripeptide-38 to cells and measured the production of various ECM components. After five days of twice-daily treatment at 2% concentration:

Collagen I synthesis increased by 105%
Collagen III synthesis increased by 104%
Collagen IV synthesis increased by 42%
Fibronectin, hyaluronic acid, and laminin-5 also showed significant increases

These results demonstrate that the peptide genuinely stimulates ECM production at the cellular level, not just in marketing claims.

Clinical Trials: Real Wrinkle Reduction

The most commonly cited clinical study involved 25 female volunteers aged 42-70 who applied a cream containing 2% Matrixyl Synthe'6 twice daily for two months. Wrinkle measurements were taken at baseline, one month, and two months using both instrumental assessments and visual grading.

The results, according to manufacturer data, showed:

Wrinkle volume decreased by up to 31%
Wrinkle depth and surface area improved significantly
Visible smoothing of forehead and crow's feet wrinkles
Lifting effect on skin texture

Individual results varied widely—some participants saw reductions approaching 100% for certain wrinkle parameters, while others showed more modest improvements. This variability is typical of cosmetic studies, as factors like baseline skin condition, sun damage, genetics, and compliance affect outcomes.

Serum Formulation Study

A more recent study published in 2020 examined a face serum containing palmitoyl tripeptide-38 (5 ppm), along with l-ascorbic acid (vitamin C, 15% w/v), tocopheryl acetate (vitamin E), hydrolyzed hyaluronic acid, bakuchiol, and a polyherbal and vitamin blend. In this open-label study, women aged 40 and older with visible signs of photoaging applied the serum once daily for 56 days.

Results showed:

Skin-roughness parameters decreased significantly by 8-9%
Redness decreased by 9%
Skin homogeneity (evenness) increased by 8%
Participants reported improvements in overall skin quality

While this study didn't isolate palmitoyl tripeptide-38's effects (the formulation contained multiple active ingredients), it provides real-world evidence that serums containing this peptide can produce measurable improvements in aging skin.

Dermocosmetic Product Study

A separate clinical study tested a dermocosmetic product containing palmitoyl tripeptide-38 in 32 women with crow's feet wrinkles. Participants applied the product twice daily for 28 days. Results showed significant anti-wrinkle effects, increased dermal density, and improved elasticity compared to baseline measurements.

What the Research Doesn't Show

It's worth noting what the published research doesn't establish:

No head-to-head comparisons with other peptides — We don't have published studies directly comparing Matrixyl Synthe'6 to other anti-aging peptides like GHK-Cu or Argireline.
No long-term data — Most studies run 2-3 months. We don't have published data on what happens with 6-12 months of continuous use or whether benefits plateau.
Limited data on concentration-response — While 2% is the recommended concentration, we don't have published studies showing whether lower or higher concentrations would be more or less effective.

These gaps don't invalidate the existing research—they just mean there's still more to learn.

Matrixyl Family Comparison

Matrixyl Synthe'6 is the third major peptide in Sederma's Matrixyl line. Each generation targets different aspects of skin aging with different mechanisms.

Original Matrixyl (Palmitoyl Pentapeptide-4)

The first Matrixyl peptide, released in the early 2000s, contains palmitoyl pentapeptide-4 (formerly called palmitoyl pentapeptide-3, or Pal-KTTKS). This five-amino-acid sequence is derived from the C-terminal fragment of type I procollagen.

Mechanism: Matrixyl signals cells to produce more collagen and glycosaminoglycans, primarily by mimicking a fragment of collagen that's released during normal turnover.

Best for: General collagen support and early anti-aging prevention.

Matrixyl 3000 (Dual Peptide Complex)

Released in the mid-2000s, Matrixyl 3000 contains two peptides:

Palmitoyl oligopeptide (formerly palmitoyl pentapeptide-3) — Similar to original Matrixyl
Palmitoyl tetrapeptide-7 (formerly palmitoyl tetrapeptide-3) — Reduces inflammation and inhibits IL-6, a cytokine involved in collagen breakdown

Mechanism: Dual approach—stimulate collagen production while reducing inflammation and collagen degradation.

Best for: Fine lines, surface wrinkles, and overall skin support. According to comparisons, Matrixyl 3000 is ideal for sensitive skin and preventative anti-aging.

Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)

Released in 2012, Matrixyl Synthe'6 takes a broader approach than its predecessors.

Mechanism: Stimulates six major ECM components, including three types of collagen and components of the dermal-epidermal junction.

Best for: Deep wrinkles, loss of firmness, and sun-damaged skin. Sources indicate that Matrixyl Synthe'6 provides more intense, targeted treatment for pronounced aging signs.

Key Differences

Feature	Matrixyl	Matrixyl 3000	Matrixyl Synthe'6
Peptides	1 (pentapeptide)	2 (oligopeptide + tetrapeptide)	1 (tripeptide)
Primary Target	Collagen I	Collagen I + anti-inflammation	6 ECM components
Mechanism	Collagen stimulation	Collagen stimulation + MMP inhibition	Multi-target ECM synthesis
Best For	Prevention	Fine lines, sensitive skin	Deep wrinkles, firmness
Visible Results	8-12 weeks	6-8 weeks	4-6 weeks
Intensity	Mild	Moderate	High

Can You Use Them Together?

Matrixyl 3000 and Matrixyl Synthe'6 work through different mechanisms, which theoretically makes them compatible. According to Timeless Skin Care, if using both in the same routine, apply them to different areas rather than layering them—for example, Matrixyl Synthe'6 on deep wrinkles (forehead, crow's feet) and Matrixyl 3000 on other areas for overall support.

There's no published research confirming synergy or incompatibility, so this recommendation is based on practical application rather than clinical evidence.

How to Use Matrixyl Synthe'6

Application Guidelines

Concentration: The standard effective concentration is 2%, based on Sederma's clinical studies. Most commercial products contain between 2-5% Matrixyl Synthe'6.

Frequency: Twice daily application—morning and evening—produced the best results in clinical trials. Evening application is particularly important, as skin enters restorative mode during sleep when cellular repair processes are most active.

Amount: For serums, 2-3 drops are typically sufficient for the entire face. Apply to clean, dry skin.

Absorption time: Wait until the product has fully absorbed—usually 1-2 minutes—before applying the next step in your routine.

Routine Placement

Matrixyl Synthe'6 is a water-soluble peptide that should be applied after cleansing and before heavier products.

Typical order:

Cleanser
Toner (optional)
Matrixyl Synthe'6 serum
Other treatment serums (vitamin C in the morning, retinoids at night)
Hyaluronic acid serum (optional)
Moisturizer
Sunscreen (morning only)

Note: Some sources recommend applying Matrixyl Synthe'6 before vitamin C, while others suggest after. There's no definitive evidence either way. If using both, allow each product to absorb completely before applying the next to prevent interference.

Combining with Other Actives

Compatible ingredients:

Hyaluronic acid — Enhances hydration, works synergistically with Matrixyl Synthe'6's HA-stimulating effects
Niacinamide — Improves barrier function, reduces inflammation, no known interactions
Copper peptides — Different mechanism (wound healing, remodeling), no documented conflicts
Antioxidants (vitamin E, resveratrol) — Protect against oxidative stress, complementary to peptide action

Use with caution:

Vitamin C (l-ascorbic acid) — Both are pH-sensitive. If using in the same routine, apply vitamin C first (pH 2.5-3.5), wait 15-20 minutes, then apply peptide serum.
Retinoids — No direct incompatibility, but both can cause irritation. If new to either ingredient, introduce them gradually and consider using at different times (peptides morning, retinoids evening).

Avoid:

Direct acids (AHAs, BHAs) in the same step — Low pH can degrade peptides. If using chemical exfoliants, apply them at a different time of day or use them on alternating nights.

Timeline for Results

Based on clinical studies and user reports:

4-6 weeks: Initial improvements in skin texture and hydration
8 weeks: Visible reduction in wrinkle depth and volume (average 31% in clinical studies)
12 weeks: Maximum benefit, with improvements in firmness and elasticity

Peptides work gradually by stimulating natural cellular processes. Unlike retinoids or acids that cause visible changes within days to weeks, peptides require consistent use over months to produce noticeable results.

Safety and Side Effects

Safety Profile

Matrixyl Synthe'6 (palmitoyl tripeptide-38) has been evaluated by the Cosmetic Ingredient Review (CIR) as part of their assessment of palmitoyl oligopeptides used in cosmetics. According to their safety assessment, in diluted form (as used in cosmetic products), palmitoyl tripeptides showed:

Negligible toxicity
No skin sensitization (no allergic reactions)
No phototoxicity (safe to use in the presence of sunlight)
Some ocular irritation in concentrated form, but not at cosmetic-use concentrations

The assessment concluded that palmitoyl oligopeptides, including palmitoyl tripeptide-38, are safe for use in cosmetics at the concentrations typically used (up to 5%).

Reported Side Effects

Matrixyl Synthe'6 is generally well-tolerated, even by sensitive skin types. Most users report little to no irritation when incorporating the ingredient into their routine.

Potential side effects include:

Mild redness (rare)
Slight dryness or irritation (uncommon)
Temporary sensitivity (very rare)

These effects, when they occur, are usually mild and resolve with continued use as skin adjusts. If irritation persists, discontinue use and consult a dermatologist.

Precautions

Patch test: Although reactions are uncommon, it's good practice to patch test any new skincare ingredient. Apply a small amount to the inside of your forearm, wait 24 hours, and check for redness or irritation before using on your face.

Pregnancy and nursing: There is no specific contraindication for Matrixyl Synthe'6 during pregnancy or breastfeeding. However, data on topical peptide use during pregnancy is limited. Consult your healthcare provider if you have concerns.

Eye area: While Matrixyl Synthe'6 is commonly used around the eyes (crow's feet), avoid direct contact with eyes. If contact occurs, rinse thoroughly with water.

Concentration: Stick to products with 2-5% Matrixyl Synthe'6. Higher concentrations haven't been proven more effective and may increase the risk of irritation.

Frequently Asked Questions

How long does it take to see results from Matrixyl Synthe'6?

Most users notice initial improvements in skin texture and hydration within 4-6 weeks of consistent twice-daily use. Visible reduction in wrinkle depth and volume typically becomes apparent at the 8-week mark, with maximum benefits seen around 12 weeks. Unlike retinoids or chemical exfoliants that work by causing controlled damage, peptides work by gradually stimulating natural repair processes, which is why they require longer to show results.

Is Matrixyl Synthe'6 better than retinol?

They're not directly comparable—they work through entirely different mechanisms. Retinoids (retinol, tretinoin) increase cell turnover, boost collagen production, and regulate gene expression, but they can cause irritation, dryness, and photosensitivity. Matrixyl Synthe'6 stimulates ECM production through cell signaling without causing irritation or requiring sun avoidance. For many people, the best approach is using both: peptides for gentle, cumulative improvement and retinoids for more aggressive anti-aging. If you can't tolerate retinoids or want a gentler alternative, Matrixyl Synthe'6 is an effective option.

Can I use Matrixyl Synthe'6 with vitamin C?

Yes, but timing matters. Both ingredients are pH-sensitive. Vitamin C (l-ascorbic acid) works best at pH 2.5-3.5, while peptides prefer pH 3.0-7.0. If using both in the same routine, apply vitamin C first on clean skin, wait 15-20 minutes for it to absorb and for pH to normalize, then apply your Matrixyl Synthe'6 serum. Alternatively, use vitamin C in the morning and peptides at night to avoid any potential interaction.

Does Matrixyl Synthe'6 work better than Matrixyl 3000?

"Better" depends on your skin concerns. Matrixyl 3000 is a dual-peptide complex that focuses on collagen stimulation and inflammation reduction—it's ideal for fine lines, surface wrinkles, and preventative anti-aging, particularly for sensitive skin. Matrixyl Synthe'6 targets six components of the extracellular matrix, making it more appropriate for deep wrinkles, firmness loss, and sun-damaged skin. Many dermatologists recommend Matrixyl 3000 for younger skin showing early aging signs and Matrixyl Synthe'6 for more advanced aging concerns.

Can I use Matrixyl Synthe'6 around my eyes?

Yes. Matrixyl Synthe'6 is safe and effective for the eye area. In fact, clinical studies specifically measured its effects on crow's feet (wrinkles around the eyes). The skin around the eyes is thinner and more delicate, so peptides are often better tolerated there than harsher actives like retinoids. Just avoid getting the product directly in your eyes—if contact occurs, rinse with water.

Does Matrixyl Synthe'6 work on all skin types?

Yes. Unlike some actives that work better on certain skin types (for example, vitamin C can be too irritating for sensitive skin, while BHAs work better on oily skin), peptides like Matrixyl Synthe'6 are suitable for all skin types: normal, dry, oily, combination, and sensitive. The water-based formulation absorbs easily without leaving a greasy residue, making it appropriate even for acne-prone skin.

Will Matrixyl Synthe'6 make me purge or break out?

No. "Purging" happens when actives that increase cell turnover (retinoids, AHAs, BHAs) accelerate the lifecycle of clogged pores, bringing congestion to the surface faster. Peptides like Matrixyl Synthe'6 don't increase cell turnover, so they don't cause purging. If you break out after introducing a Matrixyl Synthe'6 product, it's likely a reaction to another ingredient in the formulation (silicones, fatty alcohols, fragrances), not the peptide itself.

How does Matrixyl Synthe'6 compare to Argireline?

Completely different mechanisms. Argireline (acetyl hexapeptide-8) is a neuropeptide that reduces muscle contractions, working similarly to Botox to prevent expression lines from forming. It's most effective on dynamic wrinkles caused by facial movements (forehead lines, crow's feet). Matrixyl Synthe'6 is a signal peptide that stimulates ECM production to fill in static wrinkles (wrinkles that are visible even when your face is relaxed). For comprehensive anti-aging, some people use both—Argireline to prevent new dynamic wrinkles and Matrixyl Synthe'6 to repair existing static wrinkles.

Do I need to refrigerate Matrixyl Synthe'6 serums?

Generally no, unless the product label specifically recommends refrigeration. Most Matrixyl Synthe'6 serums are formulated with preservatives and stabilizers that keep them shelf-stable at room temperature. Store them in a cool, dark place away from direct sunlight and heat. Check the product packaging for the period-after-opening (PAO) symbol—most peptide serums last 6-12 months after opening.

The Bottom Line

Matrixyl Synthe'6 represents a more sophisticated approach to peptide-based anti-aging. By stimulating six major components of the extracellular matrix rather than focusing solely on collagen production, it addresses multiple aspects of skin aging simultaneously: firmness (collagen I and III), elasticity (collagen III), structural integrity (collagen IV, laminin-5, fibronectin), and volume (hyaluronic acid).

The clinical evidence, while limited to relatively short-term studies, shows genuine wrinkle reduction—around 31% improvement on average after 8 weeks of consistent twice-daily use. This puts it in the same ballpark as other evidence-based anti-aging ingredients like retinoids and vitamin C, with the advantage of being significantly gentler and better tolerated.

That said, Matrixyl Synthe'6 isn't a magic bullet. It works gradually, requires consistent use over months, and produces results that are meaningful but not dramatic. If you're looking for overnight transformation, you'll be disappointed. If you're looking for a well-researched, gentle ingredient that produces cumulative improvement in skin structure over time, Matrixyl Synthe'6 delivers on that promise.

For people who can't tolerate retinoids, Matrixyl Synthe'6 offers an effective alternative. For those already using retinoids, adding Matrixyl Synthe'6 provides complementary benefits through a different mechanism. And for anyone with deep wrinkles or loss of firmness, particularly in the forehead and eye area, Matrixyl Synthe'6's targeted approach to rebuilding the dermal matrix makes it one of the more interesting peptides currently available in over-the-counter skincare.

Medical Disclaimer: This article is for educational purposes only and does not constitute medical advice. Consult a dermatologist or qualified healthcare provider before starting any new skincare treatment, particularly if you have sensitive skin, are pregnant or nursing, or have existing skin conditions.

References

Palmitoyl Tripeptide-38 Technical Information — INCIDecoder
MATRIXYL™ synthe'6™ by Sederma — UL Prospector
Rubin MG, Elgart G, Karnik J, et al. A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos® analysis and frequently repeated auto-perception. J Cosmet Dermatol. 2020;19(11):3031-3038.
Function of palmitoyl tripeptide-38 in skin — Creative Peptides
Matrixyl® synthe'6® Product Information — Croda Beauty
Safety Assessment of Palmitoyl Oligopeptides as Used in Cosmetics — Cosmetic Ingredient Review
Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence — PMC
A Face Serum Containing Palmitoyl Tripeptide-38, Hydrolyzed Hyaluronic Acid, Bakuchiol and a Polyherbal and Vitamin Blend Improves Skin Quality — SCIRP
Matrixyl 3000 vs Matrixyl Synthe'6: Understanding the Key Differences — Skin Deva
Difference Between Matrixyl® Synthe 6 vs Matrixyl® 3000 — Depology
Matrixyl® 3000 vs. Matrixyl® Synthe'6 — Timeless Skin Care
Palmitoyl Tripeptide-38 Product Data — Cosmetic Ingredients Guide
What is Matrixyl Synthe'6 — Truth In Aging
Is Matrixyl Safe? — Timeless Skin Care

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